Lincoln Rhyme was the department's top homicide detective and leading expert in criminal forensics until an injury left him paralyzed, depressed, and incapable of working. But when a gruesome murder in Manhattan leaves detectives baffled, they call on Rhyme to help solve the mystery. Amelia Donaghy, a rookie cop whose quick thinking preserved a gruesome murder scene, is enlisted by Rhyme to be his on-the-scene forensics expert. With Amelia reluctantly acting as Rhyme's able-bodied go-between, the pair piece together cryptic clues the killer leaves behind at the scene of the crime, hoping to catch the grisly serial killer.

A man is accused of murdering his childhood love and her entire family.

A neurotic and overly-presumptuous mother accuses her family's au pair of stealing a cherished heirloom, much to the chagrin of her husband.

A man is falsely convicted of the murder of his wife. During his time in jail, he finds comfort from four women with whom he corresponds. After his second court appearance, he is finally freed from prison only to be framed for yet 2 more murders which he did not commit. With the help of his former prison guard, he once again sets out to clear his name

When a crisis threatens to destroy their high school, four teens hatch a daring plan to raise $10 million. Step one? Breaking into the U.S. Mint.

In 1950s Connecticut, a housewife's life is upended by a marital crisis and mounting racial tensions in society.

Teenage Zoe Tyler suffers from manic-depression. With a musician father who is never around life seems hard. Zoe eventually lands up in a psychiatric ward for treatment. There she meets Jake, an unstable teenager with an anger problem. They fall in love and are soon separated by their doctors, psychiatrists and parents. Fuming, Jake suddenly sees a chance for escape and takes Zoe with him, along with a few other patients. After a trip around the country, Jake and Zoe must face up to their illness and their crime.