Chief Inspector Karl Jäger is preparing for the birth of his grandchild, while his colleague Jasmin Stein is thrown into a passionate love affair. But Lola Kraft is also back after her maternity leave when the body of a car dealer is found in a villa. The safe is open, but apparently no money was stolen. What was so valuable that the son of a Russian mafia boss had to die?

A supermarket is robbed. Commissioner Karl Jäger, who happens to be present, shoots the robber and is subsequently suspended from duty because the attacker’s weapon is not found. The incident also plunges Jäger into deep psychological problems. As a result, commissioners Lola Kraft and Jasmin Stein are called in when two bodies are discovered during the night of a class reunion at the Calw Hermann Hesse High School. All 29 party guests are considered suspects. When the investigators find out that their suspended colleague was a former classmate, his memories help advance the solution to the case, which has its origins in their school days.

Inspectors Karl Jäger, Lola Kraft and junior police officer Jasmin Stein must solve the brutal murder of a hunter whose dismembered body was found in the middle of the forest. The investigation points to illegal arms trafficking and initially leads to the Reich Citizens' milieu. Another blood trail was also found at the crime scene...

Detectives Karl Jäger and Lola Kraft are investigating again. An inconspicuous family man saves a young woman from being raped and uses unexpected skills that not only attract the attention of himself, but also of the police. But it is not just his mysterious past that troubles the amnesiac victim, but also a killer squad. Who is after him? And what is the mystery of his past?

Nikolaus Kaminsky is a former police profiler who has been living in seclusion for 20 years, with no contact with the outside world. Only his neighbor's daughter Simone manages to coax him out of his shell from time to time. When he threatens the 12-year-old with a knife for no apparent reason one day, detectives Jäger, Kraft, and Hoffmann are called in. The police are actually busy with a kidnapping case, but when Kaminsky casually leads the investigators to the solution of the case, a long-forgotten case of child murders suddenly becomes relevant again. The last victim of the serial killer, who remains unknown to this day, was Kaminsky's daughter. When Kaminsky then warns the police about a new kidnapping case, the suspicion arises that the killer, believed to be dead, is back at work.

Shortly after being released from prison, an ex-convict is abducted by a masked stranger. This is a case for Inspector Jäger, who, due to a lack of work in the Calw homicide division, has to assist colleagues in other departments.

This time, Tatort Calw takes us to the stage, the world's greatest stage. During an amateur theater performance, a version of Romeo & Juliet "translated" into Swabian, a shot is fired according to the script. But the bullet was not a blank. The result: undertaker and amateur actor Günther Jourdan lies dead on the stage. A new case for Calw detectives Jäger, Kraft, and Hoffmann, who now find themselves confronted with a multitude of quarrels, motives, and suspects within the theater troupe. Secret affairs, property disputes, pregnancies, and personal animosities. The theater people are like a prime-time soap opera on private television. However, when the alleged perpetrator is identified, there is a surprising twist.