Four teenagers sneak out of their houses one night and walk across town to confront the school bully, who happens to be looking for them as well.

You Lose You Die follows sociopathic tech expert, Mr. Fantastik, who runs a popular show on the dark web with two other sociopathic tech experts, Ms. Perfect and Mr. Creep. On the show, thousands of viewers vote on games and challenges for prisoners to participate in. If the prisoners lose, viewers vote on the weapons the sociopaths use to kill them.