Set in 1964, a three-day journey along Route 66 begins when Bobby Falls, a 19-year-old serial killer, hitches a ride with Jim Goodwin, a celebrity animal handler travelling with his precious cargo: his TV chimpanzee, Spanky.

St. Nick is the story of a brother and sister on the run. They've left their home for some unknown reason and are living in the woods, hiding in barns and sheds, doing what they can to survive. As the bitter Texas winter sets in, they strike up residence in an abandoned country house and, for a brief, happy period, manage to escape the harsh realities of their circumstances.

At the dawn of the space-race, two radio-obsessed teens discover a strange frequency over the airwaves in what becomes the most important night of their lives and in the history of their small town.