After a car crash, Tammy and injured basketball players are hospitalized. When a nurse kisses dying Tammy, an alien infection spreads through the hospital staff and patients. The facility is quarantined as infected people seek sugar.

The friends Emmett, Freddy, Marie, Kevin and his reluctant girlfriend Jessie decide to spend the Halloween night in an abandoned hospital. Meanwhile, the younger Allan meets the old friend of his father Arlo Ray Baines and asks him to help to find his vanished sister Meg in the same spot. The two groups meet each other in the mental institution section on the haunted third floor.

In California, Zack owns the "Breakingtime Billiards", a store that sells pool tables and game room supplies. He works with his girlfriend Jennifer; the sexy seller Tara; the installer of pool tables and best friend, the wolf David, and his idiot assistant Eddie. After having a threesome arranged by Jen with Tara, Zach breaks up his relationship with Jen, in spite of her bringing him up all the time. He tells his sexual experience to David while Jen asks for an advice to her psychologist Dr. Bob Johnson in his radio show. Along the day and after the visit of many peculiar clients, Zack concludes that Jen is his dream girl.

Two Arizona girls head out to the Malibu beaches for a springbreak of partying and fun in the sun.

A high school outcast who lives in a trailer with his mother finally meets a friend. He wants to ask her if they can go the next step, but then sees her kissing another boy at a party. He runs home only to find his mother having sex with a drunk. He starts yelling, but is countered by the drunk when he suffocates him and makes him look like he hung himself. The scarecrow comes in when the boy's soul is pushed into it. He goes out for revenge.

After being abducted by extraterrestrials, Jean and her friends are committed to a top secret government-run mental institution to undergo tests and be brainwashed.

When Spence and Hogan graduate from college, life is bleak. They have to work for heinous divorce lawyers that torture them with gruesome jobs. Spence has a girlfriend from hell, and Hogan just wants to start his life. As luck would have it, these two young men are presented with an opportunity, and develop a club of young men devoted to older women, whom they call “Cougars.”

An Eastern European tourist unexpectedly finds himself stranded in JFK airport, and must take up temporary residence there.