At seventeen, girls are all about looking good, dressing right and making out with the cutest boys. Or they're like Luka, who's an ace in boxing and couldn't care less about her looks or her appeal to boys. When she breaks a schoolmate's nose, her parents send her off to boarding school to acquire some ladylike manners. There she's mistaken for Frankie, a boy who hasn't shown up, and takes on his identity. With her boxing skills, she instantly wins over her three roommates Chico, Toby and Jo, and strikes up a particularly close friendship with Chico. Her uncompromising honesty and loyalty to her new friends, however, soon get her into trouble with the headmistress and her nephew, the school bully.

In 1933 Nuremberg, successful Jewish businessman Leo Katzenberger owns an apartment building and runs a shoe store. A devoted family man, he has a good relationship with his loving wife Claire. As the climate in Germany grows increasingly dangerous, bombshell Irene moves to the neighborhood. After forming an unlikely friendship, his relationship with Irene is immediately regarded with suspicion.

In the sequel of "Ants in the Pants" we again meet Flo and his friends.

Flo is not quite a normal teenager: While all his friends only think about sex he can't even pronounce the word "S - E - X". But everything changes completely when one morning Flo wakes up from a strange call. His penis, excited for the first time, begins to talk to him. He claims that Flo severely neglected him for 15 years and it's time to release him.