Max, an aimless middle-aged man, travels to Brussels. As he wanders the city streets, he meets three unlikely companions, with tensions rising among the group each passing hour.

The antiques shop Gerard owns should help him to get rid of his financial problems. He dreams of writing the most important Dutch novel ever. Unfortunately he spends money like water. As a result he is constantly broke. His sister Ingrid is married to Pierre. She wants a child but he refuses. While Gerard is willing to consider leading a normal life, a wish mainly expressed by his parents, Ingrid's marriage falls apart.

An Antwerp journalist finds his daily life increasingly disrupted by unexplained phenomena, such as an authentic letter from 1919 that refers to an event taking place at a much later date. Because these disturbances are consistently linked to the name “Joachim Stiller,” the journalist becomes obsessed with it. The resolution, which is closely tied to his traumatic experiences from the Second World War, takes place with a psychiatrist—and later at an abandoned railway station in an Antwerp suburb. Interwoven with this is a subplot about an Antwerp art dealer who believes he can become rich through a new form of painting. To achieve this, he takes a mentally disabled artist hostage. The narrative also follows various romantic entanglements involving the journalist, which ultimately lead to his happy experience of fatherhood.