In 1942, Red Army officer Nikolai Kiselyov receives orders to evacuate over 200 Jewish women, children, and elderly men facing brutality and death in Nazi-occupied Belarus. These exhausted, starving, terrified and bereaved people, deeply scarred by the horrors they have witnessed, must trek hundreds of kilometers along forest paths to regain hope of survival and faith in the future.

Weeks after giving birth to her first child, a young Baalat Teshuva—a newly religious woman—arrives at the home of her Rebbetzin, claiming that her husband has been replaced. He looks and sounds exactly the same—but something inside of her knows he is not the man she married. My One and Only is a multi-character mystery drama that explores how people change in relationships, the difference between falling in love and staying in love, and what we do when the person closest to us becomes a stranger.