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Dissolute Abel Beer, with the help of his debt collector friends - usurers, swindles a Prague Doctor Jakub Hlohovský out of a quiet house in Malá Strana. Jakub, familiar with the secrets and effects of various medicines, uses them to make himself look dead.
During a pogrom against Jews in a village, an innkeeper is killed, his daughter is put in a convent after being crucified, and her illegitimate child, who later grows up to be a student, is placed in the care of a guardian.