Clawdeen Wolf, half human and half werewolf, has recently started attending Monster High, a school for monsters in all forms. After quickly befriending her classmates Frankie Stein and Draculaura, Clawdeen feels like she has finally found a place where she can truly be herself, or so she thinks. Soon, a devious plan to destroy Monster High threatens to reveal her real identity and Clawdeen must learn to embrace her true monster heart before it's too late.

As they enter sophomore year at Monster High, Clawdeen Wolf, Draculaura and Frankie Stein face new students, new powers, and an even bigger threat that could not only tear their friendship apart but could change the world forever.

When the pressure to be royal becomes too much for Mal, she returns to the Isle of the Lost where her archenemy Uma, Ursula's daughter, has taken her spot as self-proclaimed queen.