A group of diverse individuals are suddenly taken from their homes and flown via helicopter to a futuristic bomb shelter in the desert, nearly two miles below the surface of the Earth. There they learn that a nuclear holocaust is taking place and that they've been "chosen" by computer to survive in the shelter in order to continue the human race. The shelter is designed to allow the people to exist underground comfortably for years, but they are faced with a threat nobody could have predicted: a colony of thousands of bloodthirsty vampire bats finds a way into the shelter and launches a series of vicious attacks where they claim the humans one by one.

Daniel Boone leads settlers into Kentucky, but must battle Shawnee Indians who have been persuaded by a French renegade that Boone and the settlers are there to kill them and steal their land.

An American actress travels to Mexico to make a movie and brings her daughter with her. Upon arriving in Mexico, she is spotted by a drug dealer who also heads a kidnapping ring. He plants one of his drug-addicted "customers" with the actress as her nanny in order to be kidnap the child for ransom, but things don't work out as planned.

In 1883, the Apache Indians lead by Geronimo reluctantly surrender to the attacks of American and Mexican troops, in exchange for a territory and food for their warriors. Soon though, Geronimo escapes the camps and declares war against the Americans.