A flight attendant's inner turmoil is triggered on a late night flight.

What do you say fellas...ready to blast off? Words to live by, according to six blissfully reckless friends who come together for a lost weekend wedding reunion of drinking, bowling, fighting, snorting, puking, screwing, writing bad novels, getting spanked by a psychotic preacher, hailing extraterrestrials and finally...learning that it takes more than a few days to achieve total world domination.

A celebrity couple attend a wellness retreat only to find that they are the guinea pigs in a life changing experiment.