A Retrovirus, which was conceived as a tool for industrial genetic engineering, has gotten out of control and is spreading rapidly. While it crosses all organisms within our ecological system completely indiscriminately (mixing plant with animal and humans) most plants prove more resistant because of their complex DNA. However, the simple genes of the plants lead humans to become grotesque mutations, in most cases even to death. Within one week, 90% of mankind are either extinct or no longer human. However, a small fraction of the earth?s population remains immune to the virus and must survive in this new and constantly changing ecological system. Tom cellar is one the survivors and on an old military base in the Eifel he has entrenched himself. Further survivors come together and succeed in carving out a life in this new world. But the GMOs - the ?genetically modified organisms? - constantly develop themselves further, and soon the fence of the base offers no more protection.

Where shall we put grandma? Her permanently anxious and stressed daughter, Marie, knows exactly where: the neighbourhood’s idyllically situated retirement homem where she can find friends of “her own age”. But Granny has other ideas: She wants to see the Pope in Rome, and no one can stop her plan. She wants to finally confess a troubling sin to the highest possible power. She resolves to make the journey alone, and ends up one day on the doorstep of her granddaughter, Martina. What she doesn’t know is that Martina has a secret too, and that a private audience with the Pope is virtually impossible for mere mortals. Together with sly bon vivant, Lorenzo, the three set off on an adventure – but their attempt to receive a Papal blessing almost ends in disaster.