Adapted from a popular novel with the same title, Karmila tells a story about a medical student who becomes pregnant after sexually assaulted at a party.

Harun is a successful and busy surgeon who has no time for his family. One day he meets a desperate woman who wants to commit suicide. He takes her into a house and she becomes pregnant. His wife, who is running out of patience, reveals Harun's poor behavior. Harun then gets angry. He steals his wife's property and runs away with his mistress.