The event was headlined by a heavyweight bout, contested by the former UFC Heavyweight champion Fabrício Werdum and Renan Ferreira. In the co-main event, the 2019 PFL Lightweight champion Kayla Harrison fought Mariana Morais.

UFC Fight Night 222: Pavlovich vs. Blaydes was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on April 22, 2023, at the UFC Apex facility in Enterprise, Nevada. A heavyweight bout between Sergei Pavlovich and Curtis Blaydes headlined the event.

UFC Fight Night 228: Fiziev vs. Gamrot was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on September 23, 2023, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A lightweight bout between Rafael Fiziev and former KSW Featherweight and Lightweight Champion Mateusz Gamrot headlined the event.

UFC on ESPN 40: Santos vs. Hill was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on August 6, 2022, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A light heavyweight bout between former UFC Light Heavyweight title challenger Thiago Santos and Jamahal Hill headlined the event. The heavyweight and women's flyweight finals of The Ultimate Fighter: Team Peña vs. Team Nunes took place at the event.

UFC on ESPN 53: Ribas vs. Namajunas was a mixed martial arts event produced by the Ultimate Fighting Championship that will took place on March 23, 2024, at UFC Apex in Enterprise, Nevada, United States. A women's flyweight bout between Amanda Ribas and former two-time UFC Women's Strawweight Champion Rose Namajunas headlined the event.

UFC on ESPN 60: Lemos vs. Jandiroba was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on July 20, 2024, at the UFC Apex facility, in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A women's strawweight bout between former UFC Women's Strawweight Championship challenger Amanda Lemos and former Invicta FC Strawweight Champion Virna Jandiroba headlined the event.

UFC on ABC 8: Hill vs. Rountree Jr. was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on June 21, 2025, at the Baku Crystal Hall in Baku, Azerbaijan. A light heavyweight bout between former UFC Light Heavyweight Champion Jamahal Hill and former title challenger Khalil Rountree Jr. headlined the event.

UFC Fight Night 261: Oliveira vs. Gamrot (also known as UFC Fight Night: Oliveira vs Gamrot and UFC on ESPN+ 119) was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on October 11, 2025, at the Farmasi Arena, in Rio de Janeiro, Brazil.