After having narrowly escaped an attempt on his life at the hands of a psychopath, detective inspector Takakura quits active service in the police force and takes up a position as a university lecturer in criminal psychology. But his desire to get to the bottom of criminals’ motives remains, and he does not hesitate long when former colleague Nogami asks him to reopen an old case.

Following the events of Ju-on: The Beginning of the End, Mai, the older sister of elementary schoolteacher Yui Shono, goes to look for her sister, who disappeared after a year while working in an elementary school. Mai soon discovers the Teriyaki household who tells her about what happened to her sister. Mai will now uncover the dark secrets of Ju-on and will try to end the curse once and for all.

As the sole survivor of a horrendous and rather mysterious accident, teenage Mitsuko's day is off to a bad start. An unstoppable force of nature, a doomed field trip, and a strange case of amnesia easily coexist in a bizarre parallel universe, where a desperate Mitsuko is always on the run from something inexplicable, intangible, and utterly deadly. However, amid piles of fresh corpses, mounds of scorching bullet shells, and rivulets of fragrant adolescent blood, Mitsuko must fight to stay alive, before her already messed-up day becomes even stranger. But one question still remains: who or what is the enemy?

A school teacher visits the home of a boy who's been absent from school for a long period of time, unaware of the horrific tragedy which occurred in the boy's household many years ago.