The subject of this film, which takes an analytical look at the life of all of us with an analytical eye, is the evil microbe that has slowly infiltrated the organism of the Czech nation. Through the intertwining fates of three couples, it evokes domestic life before November 1989, burdened by a suffocating atmosphere of unfreedom, and after November, when relatively nothing has changed because people have not changed. The bleak conclusion suggests that the plague epidemic is still ongoing.

Dana is young medical student with no self esteem, she can't deal with life, people and even not with herself. After her boyfriend leaves her, she changes to selfish woman, manipulating people and making them to serve her. She plays with her husband, neighbors and friends - for her own good and for fun.