Five seemingly unrelated people decide to take huge risks in their personal lives in an effort to find happiness.

Dorothy Parker remembers the heyday of the Algonquin Round Table, a circle of friends whose barbed wit, like hers, was fueled by alcohol and flirted with despair.

Roger Greenberg, a failed musician now making a living as a carpenter in New York, returns to Los Angeles to house-sit for his brother. He's stranded there—since he doesn't drive—until his brother's assistant, Florence, comes to his rescue. She's as much a lost soul as he is, and the pair form a significant connection—giving Roger a much-needed reason to be happy.

A devoted nurse falls in love with a formerly comatose patient who has lost his sense of touch.

Two strangers refuse to leave the seaside home of a couple, which leads to sexual tension and crime.

Ben, Duncan, and Mary are the three main characters in "Duncan Removed", a film that asks the question, what if that little voice inside your head belonged to someone else?

While celebrating their reconciliation and six years of marriage, American actress Sally Nash and British novelist Joe Therrian receive their close friends, some colleagues and their next door neighbors in a party. Under the effect of Ecstasy, revelations are disclosed and relationships deteriorate among the group.

Mike Sullivan works as a hit man for crime boss John Rooney. Sullivan views Rooney as a father figure, however after his son is witness to a killing, Mike Sullivan finds himself on the run in attempt to save the life of his son and at the same time looking for revenge on those who wronged him.

A smooth-talking ad executive attributes his remarkable success with women to his ability to manipulate their emotions from the moment he first meets them. When his teenage nephew drops in for a visit, he soon learns that his approach isn't as foolproof as he thought when he attempts to teach the boy how to pick up women.

Sadie looks up to her older sister Georgia, a successful folk singer. Unfortunately it is this very obsession — coupled with her self-destructive tendencies and rampant drug abuse — that keeps her spiraling down the drain.