Welcome to the front lines of AIDS activism, where the latest enemy raids are being run by a band of unlikely warriors: two drag queens, an HIV-positive man with tiny gemstones dotting his bald head, and his HIV-positive sister.

A discount store clerk strikes up an affair with a stock boy who considers himself the incarnation of Holden Caulfield.

Loyalty amongst friends isn't always the case, when your life is on the line.

Letty Mayer, young and beautiful, has a cherished job as a teacher, a successful attorney boyfriend, and a tight knit family that is excited about her sister's impending wedding. But inside Letty there¹s an anxiety that¹s building. Suddenly the pressure of Letty's world overwhelms her and she suffers a devastating nervous breakdown. Institutionalized, she meets Michael, a schizophrenic who has been in and out of hospitals his entire life. Although major obstacles exist, Letty and Michael throw caution to the wind to pursue an intense new love as Letty finds herself torn between a safe past and a daring future...

Alix is taken in by a photographer, Digna, who despite her friends' protests, tries to help Alix piece her life back together and overcome her addictions.

Feeling abandoned by her therapist who's gone on an extended vacation, beautiful Lindsay gets help with her fear of commitment from an ad hoc support group formed by other New Yorkers also left high and dry by their shrinks. But when her pals dare her to date fellow group member A.J., Lindsay begins to wonder if she's finally found her match.

With help from U.S. Rep. Corrine Brown, Tammi Chase (Rachael Leigh Cook) fights to free her mother (Barbara Hershey) from an Ecuadorean prison where she has been wrongly imprisoned for drug trafficking.

"Washington Heights" tells the story of Carlos Ramirez, a young illustrator burning to escape the Latino neighborhood of the same name to make a splash in New York City's commercial downtown comic book scene. When his father, who owns a bodega in the Heights, is shot in a burglary attempt, Carlos is forced to put his dream on hold and run the store. In the process, he comes to understand that if he is to make it as a comic artist, he must engage with the community he comes from, take that experience back out into the world, and put it in his work.

When Lou Bloom, desperate for work, muscles into the world of L.A. crime journalism, he blurs the line between observer and participant to become the star of his own story. Aiding him in his effort is Nina, a TV-news veteran.

When Stuart learns that his British ex-girlfriend is planning to visit Los Angeles with her husband, he sets out to impress them with his glamorous lifestyle, enlisting a flaky Russian model he’s just met to play the role of his beautiful girlfriend. What could go wrong?