Author Otto Dean braves his fears of impending death as he sets out to write a novel opposing the controlling presence of heartless artwork & propaganda in an alternate 1980s America after being recognized for his opinion piece in the newspaper. Upon visiting a local art hot spot and speaking with a woman named Lorelei, he learns of recent murders in the area & encounters an uncanny resemblance between his own recurring dreams and a local artist's work, leading him down a further rabbit hole as he tries to catch hold of the elusive artist Inez Sabalenka.

A story of guilt and acceptance. Fishbone follows Alonzo, a young male struggling with conflicts on various sides of his life. Alonzo grapples with his parent's separation, as well as his own personal feelings about himself. This reality tears him apart, depicting how the seriously the many moving parts of one's life can affect them. In the end, Alonzo resorts to taking his own life, leaving behind his unacquainted friends to question if their actions had a direct affect, and later having to accept that this is their new reality. The two friends, Jeremy and Luca, are different, yet are united through their mutual friendship with Alonzo. The story is told through fragmented memories of Alonzo from the two friend's perspectives as they try to find acceptance amidst the loss of their friend.