Brooke Meadows, fashion model and actress from New York City goes on an excursion in the country for a photoshoot, where things take an unexpected and sobering turn.

A crack-pot scientist aligns with the Axis of Evil to bring down the United States with EMP blasts, toxic zombification gas and by unleashing the ultimate undead killing monstrosity: the Z-REX. When a hot-wired militia squad and a crew of college hipsters are thrown together to do something about it, chaotic Predator-Thunder action runs amok.

Two brothers posing as paramedics kidnap their victims and harvest their organs for the black market. That is until they kidnap a woman they find impossible to kill and it turns out she has more power over them than they over her.