The strange comedy film of two close brothers; one, Wilbur, who wants to kill himself, and the other, Harbour, who tries to prevent this. When their father dies leaving them his bookstore they meet a woman who makes their lives a bit better yet with a bit more trouble as well.

A young drifter working on a river barge disrupts his employers' lives while hiding the fact that he knows more about a dead woman found in the river than he admits.

Serial killer Molly Keller, along with a few insane youngsters agrees to be a trail subject for an unconventional experiment. But, the experiment turns unsuccessful and the subjects begin to die.