Paralyzed from a crash, Nicola falls for his physiotherapist Lucia. Franco and Manuela seek fertility treatment in Barcelona. Filippo and Fosco, a gay couple, plan their wedding. Ernesto, a waiter, has an affair with Spanish cook Cecilia.

Chloe begins to work in a new plant of his hospital, hematological oncology. She is a nurse and at first she is overcome by the situation until she meets Laura, a patient who will leave her mark.