Invicta FC 48: Tennant vs. Rubin was a mixed martial arts event headlined by Taneisha Tennant defending her bantamweight championship against Olga Rubin. The co-main event was set to feature Katharina Lehner fighting Talita Bernardo, but Lehner withdrew from the bout and was replaced by Yana Gadelha. Mallory Martin pulled out of her fight against Kyra Batara and was replaced by Valesca Machado.

Invicta FC 50 took place Wednesday, November 16, 2022 with 7 fights at Reelworks Denver in Denver, Colorado.