Set against the backdrop of the infamous Theatre Grand Guignol the story revolves around iconic actress Paula Maxa - the most famous of the Grand Guignol's leading ladies and the titular Most Assassinated Woman, who was graphically slain on stage multiple times a day.

Jessica is the leader of a group of lost boys with a violent past who now seek peace and harmony. She is the only one to have ever brought them love and understanding. They only wish to create a world where they can live in peace together, and forever.