On the night of her 40th birthday, Inge, a morbidly obese woman, has a midlife crisis. She realizes that her needy husband, Fritz, is more dangerous and deranged than he appears. His years of physical and mental manipulation, through the use of food and their relationship, all comes to the ugly surface. Inge gets inspired to stand up for herself after watching a marathon of her favorite trashy soap opera, taking the melodrama to heart. She plays Fritz at his own game of manipulation and unravels the cold and grotesque truth of their relationship, pushing both of them to their absolute limits.

Returning to the gym after being out of commission due to his father's death, Recardo "Flex" Reverte, a glory hungry bodybuilder, decides to pick up his training again to attain his ultimate physique with a close friend of his father's, Beef Cake, a hulking mass of muscle. Flex soon finds out that Beef Cake follows his father's training regime to a tee, using brutal abuse to push him to his absolute limits. Flex's girlfriend, Mari, tries to help Flex realize that he needs to stand up for himself and develop his own mindset. Flex's polar opposite influences start to take a toll on him, causing him to lash out and spiral into utter madness.