A young female limo driver meets a young male hooker who says he just accidentally killed his "John". They drive around the city looking for the client's girlfriend with the hooker in the trunk.

Isolated in his austere penthouse overlooking Central Park, obsessive Wall Street data analyst Richard Boca sees ominous patterns. His computer models are behaving erratically, as are the swarms of mosquitos breeding in his apartment, an infestation that attends his psychological meltdown.