A tall, skinny boy obsessed with traffic cones, a lesbian Adam and Eve, a wise bearded man, and the self-proclaimed King of the Sea all wander about the surreal landscape of GLAMARUS, watched over by a man who lives in a television set.

Two sisters are thrown out of their isolation and onto opposite coasts of America by a terrifying cosmic entity. On their quest to reunite they discover their own supernatural abilities and meet many strange characters.