The once happy couple, Prakasan and Sujatha bicker, and fight after the arrival of the orphan child. What is the reason?

Marykutty, a single mother, lives alone with her child. However, her life changes when she crosses paths with Louis, a man with mild autism.

Rajan, though successful in his job, but his family life is not so happy. His wife, Nalini, aspires for a fellowship in Harvard University, US, leaving behind her husband and kid, Babumon. When his father, Madhavan, a retired school teacher, is down with ailment, Rajan along with his family returns to his ancestral home. Rajan's elder sister, Vishalam, younger sister, Seethalakshmi & husband Padmanabhan also arrive to meet their father, as his health condition was serious. Madhavan's daughters and in-laws were busy in their own ways, as they don't wish to spend many days with their dying father. In his sickness, Madhavan expresses his wish to meet his niece, Ammukutty, Ammu arrives and took care of her dying uncle. Madhavan's children except Rajan leaves as Ammu was there to look after their father. Rajan remembers his young days of romance with Ammu.

The film follows underworld don Vincent Gomas (Mohanlal) and his rivalry against the Kerala Home minister N. Krishnadas (Ratheesh).

Seetha's father forces her to marry against her wishes and she is forced to remarry, when her husband dies. She is caught in a struggle as she tries to unite with her lover. Will Seetha ever be happy?

Kattathe Kilikkoodu movie is a story about an unhappy marriage that unravels in a bad way.