Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.

Rhonda, a big-haired bankteller from Brooklyn, encounters Travis, naked, suicidal and about to jump off the Brooklyn Bridge. Mistaking him for her perfect man, she stalks him all the way to Danton, Texas. Along the way she slowly comes to realize he is gay and is despondent over the AIDS-related death of his former lover. An alliance, and eventually true friendship, is formed between this extremely odd couple as they embark upon a 'treasure hunt' - with clues provided from beyond the grave.