Danny Mitchell and his canine pal Rusty befriend blind girl Penny Moffatt. Feeling cheated by life, Penny resists all efforts to cope with her handicap. But with Rusty's help, the girl gains a new lease on life and agrees to adopt a seeing-eye dog.

After several female motorists begin disappearing en route to Twin Falls, a Hollywood screenwriter and the cousin of his bride-to-be discover that they've all been abducted by the mysterious Dr. Marlowe, who is attempting to resurrect his dead wife.

A deranged artist who may have murdered his wife is investigated by the Whistler.

The discovery of a perfectly preserved caveman prompts a mad scientist to attempt a daring brain transplant.

A woman who refuses to become involved with a dedicated police officer unknowingly dates a man who is in cahoots with a criminal mastermind.

A happily married woman sees a psychoanalyst and develops doubts about her husband.

Mary Rafferty comes from a poor family of steel mill workers in 19th Century Pittsburgh. Her family objects when she goes to work as a maid for the wealthy Scott family which controls the mill. Mary catches the attention of handsome scion Paul Scott, but their romance is complicated by Paul's engagement to someone else and a bitter strike among the mill workers.

The Falcon travels to Mexico where he gets involved with murder and a mysterious painting.

Blackie is the natural suspect when an expensive pearl necklace is stolen while he is supposed to be guarding it.

Henry Aldrich wants to win a trip to Alaska.