Lovers & Murderers is about the ongoing war between those who have and those who want to have what the others have. The have-nots see themselves as poor victims trying to get for themselves what is justly theirs. But when the have-nots become haves, they continue to see themselves as victims of the hordes baying for what is justly theirs, and they have neither the energy nor the security to enjoy what they have obtained. The movie takes place in the microcosm of a small apartment building. The principal goal of the young people who share rooms in the building is to move into their own room and, some day, a real apartment. They scheme to get what they're after: form short-lived alliances, petition, frighten, marry, become pregnant, anything that might work. Lovers & Murderers presents Páral's vision of mankind caught in a cyclical process in which ideology pales before the pettiness, cruelty, and self-justification of human nature.

The film is based on real events – in 2005 Viktor Kalivoda murdered 3 random strollers he chanced upon in the forests in Czechia. The case received much attention for its lack of motive. After his arrest, Kalivoda confessed, but did not reveal his motive. The film will closely observe one year in his life leading up to the murders and his arrest.

Anna, a 16 year-old girl from the sticks, trades her military education for life in the big city Running away to Prague opens a whole new world where she drinks her first cappuccino and meets the kind of people she has only seen in movies.