A man gets involved in a murder and his life is radically transformed. He decides to return to his hometown to find his family and an old love. Unfortunately, the police and some drug dealers start harassing him until the man decides to disappear completely.

A gritty tale of survival set against a city ripe with violence and corruption. The Naked City tells the tale of Alfonso and Aurelia, who with their infant daughter flee the scene of a traffic accident they inadvertently caused, leaving several people seriously injured. On the run, they check into a hotel in a different part of the town. By coincidence, or fate, the hotel is about to be attacked by a violent gang, who resume to hold everyone hostage, moving room to room raping, killing and brutalizing the guests. When it is turn to visit with the young couple it is their time to decide to succumb to the violence, or fight back.

1941, Jose Antelmo Cruz regrets his past while writing a novel and falling in love with a prostitute.