Picking up immediately after the events in Resident Evil: Retribution, Alice is the only survivor of what was meant to be humanity's final stand against the undead. Now, she must return to where the nightmare began - The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.

Three detectives become embroiled in a tense struggle after a tragic accident that leaves a child in critical condition. One is guilty of a crime, one will try to cover it up, and the other attempts to expose it. How far will these men go to disguise and unravel the truth?