Notorious Baltimore criminal and underground figure Divine goes up against Connie & Raymond Marble, a sleazy married couple who make a passionate attempt to humiliate her and seize her tabloid-given title as "The Filthiest Person Alive".

The Cavalcade of Perversion, a traveling freak show, acts as a front for Divine, who is out for blood after discovering her lover's affair.

Shot on 8mm, and featuring the introduction of Divine, John Waters' sophomore film is a plotless collage of random incidents involving sex, drugs, religion and The Wizard of Oz, it was shown with an equally random soundtrack mixing “obnoxious radio advertisements, rock 'n' roll and press conferences with Lee Harvey Oswald's mother”. It was shown three times publicly, but never released commercially.

A day in the lives of a hit-and-run driver and her victim, and the bizarre things that happen to them before and after they collide (sexual assault by a crazed foot-fetishist, visions of the Virgin Mary, strange chicken-foot grafting operations).