On her birthday, Mery receives the worst news: her husband died in a confusing road accident. Meanwhile, Román, the boyfriend of Mery's teenage daughter, Celina, was involved in the accident. The processes of grief and how to deal with guilt as a teenager come together to tell the story of survival in "The Last Birthday."

Gustavo Alsina is a young writer who arrives at his aunt and uncle's house to find inspiration for a new novel. There, he meets Marina, a psychiatric patient twenty years his senior who escaped from the clinic run by Rubén Alsina, his uncle. Marina believes she is the character in a book she carries like her Bible, and her goal is to find the God who wrote her destiny before the final chapter arrives. The death of a nurse at the clinic is key to this film. Romance and suspense come together to tell this story.

Juan, a 14-year-old teenager, the only child of separated parents. One day, escaping from thieves, he hides inside a shed, unaware that Germonio, a man who, it turns out, locked himself inside more than ten years ago and no one has seen him come out, lives there. Juan and Germonio, due to their ages, are very different, but they have more in common than they think. A blue flower, a candle that won't light, and a journey to the depths of their soul are fundamental elements that weave this story together.