Two brothers who own a buffalo farm near Caserta attempt to resist the pressures of local mobsters who want to turn their land into an illegal landfill.

After reuniting with his first mentor Bruno and receiving his latest mission, an exiled Ciro is left to fearlessly confront whatever comes his way, navigating a new chapter of gang warfare while grappling with devastating memories of loss and trauma. Weaving between his past as an orphan in Naples' cruel underworld and present as a hardened, cunning assassin with nothing left to lose, Ciro is plunged into the cold, dark depths of a world where immortality is just another form of damnation.

Laura Rush, director of a luxury New York wine shop, has launched a campaign to buy Italian wineries to unify under her brand. Things become tangled when beautiful Anna Monti, a former top model, arrives in Italy.