After finding her sister dead, Maria tries to find out who or what is to blame.

Part of the artificial-creature series encompassing Der Golem (1914 and 1920), Alraune (1918, 1928, 1930) and Metropolis (1926), 'Homunculus' was the most popular serial in Germany during World War I even influencing the dress of fashionable Berlin. Foenss, a Danish star, is the perfect creature manufactured in a laboratory by Kuehne. Having discovered his origins, that he has no 'soul' and is incapable of love, he revenges himself on mankind, instigating revolutions and becoming a monstrous but beautiful tyrant, relentlessly pursued by his creator-father who seeks to rectify his mistake.

Richard Ortmann the artificial man (Homunculus) has become the head of the corporation that represents the capital and power of the country, but he has stopped believing in human love. All the more clear is his goal now: the annihilation of mankind.

Thérèse’s husband, Camilo, is sickly and egocentric, and when the opportunity arises, Thérèse enters into a turbulent and sordidly passionate affair with one of Camilo’s friends, Lorenzo.

The young Anselmus Aselmeyer fulfilled a long cherished dream: He travels to Venice, the city of his dreams. Once there, the porter Pipistrello directs him immediately to the hotel of his boss, and Anselmus lands in the middle of a wedding party. Mestre Mangiabene, a wealthy oilman, marries the beautiful but completely depleted Marchesina dei Bisognosi. But the secretly loves an officer.

A beautiful young innkeeper sets her sights on marrying a count.

The young sculptor Cramer is inspired by the idea of ​​modeling a statue of Aphrodite that reflects the beauty and perfection of the female body. He found his ideal model in the happily married Frau von Versen. After initial hesitation, the lady, flattered by the offer, agrees to be a model. But suddenly she is overcome by moral concerns, because as the wife of a respected legation councilor, this could cause social misunderstandings.

When a wayward nun, Megildis, deserts her convent with a knight, a statue of the Virgin Mary comes to life and takes place of Megildis, who makes her way through the world and its many vicissitudes.

Paolina is the illegitimate daughter of the Duke of Vallenza, and lives as a beggar. She meets with Nunzio, a blind man who plays violin, exploited by his stepfather, and the two fall in love. The old Duke, remorsing, tries to find his daughter but he doesn't manage and leaves everything to his latest concubine, Livia, while Nunzio and Paolina will live in misery. The only copy of this film was destroyed in World War Two