During the Covid-19 lockdown, a film crew is shooting an adaptation of Camus' La Peste. Reality and fiction start to blur between each other.

A man moves his two daughters to Italy after their mother dies in a car accident, in order to revitalize their lives. Genoa changes all three of them as the youngest daughter starts to see the ghost of her mother, while the older one discovers her sexuality.

Based on the tragicomedy written by Edoardo de Filippo in 1931, Christmas at the Cupiello's captures a life episode of a middle-class Italian family around Christmas. Shot in Neapolitan language, the movie has a whimsical charm.