Teenage Elsa has leukemia, and she needs a bone marrow transplant immediately. The only compatible donor? Someone she’s never met and whose name she doesn’t even know: her father. But thanks to Edo, a boy her age she met in the hospital, outgoing and irreverent, she decides to go on and find that man. Apparently, Elsa and Edo have nothing in common except for the illness they both share, but the journey they embark on together will change their lives forever.

Mid-1980s Italy. 12-year-old Aida suspects her father of shady dealings due to his frequent business trips and unexplained absences. She teams up with new friend Daniel to investigate Adriano's secretive import-export job.

Englishman Adam and his American bride Sarah are about to embark on the romantic honeymoon of a lifetime in Venice, Italy. But when the newlyweds’ trip is gatecrashed by Adam’s excessively needy best friend, Ed, it inadvertently turns their perfect lovers’ holiday into a complete disaster.

Cristina Comencini defines the film as a "thriller of the soul." It's the story of a woman who returns to Italy from the US to attend the funeral of her late father, an American admiral living in Naples. Here she meets a man who seems to know too many things about her.