Gaetanos the destroyer of worlds and his army are willing to do anything to obtain the stone of power and become the undisputed rulers of the universe. The situation is critical and everything seems lost, the world superpowers don't know how to react and are asking for help from the only people who are able to reverse this situation: the Italians. Misfits, criminals, witches and cockroach men take up the call to arms and take to the field to do what we've always done best: solve problems with style.

The Lady (or Signora) of the title is a mysterious matron who lives in a crumbling mansion. Six catering trainees are brought to the castle upon its conversion into a resort hotel. They are ordered to prepare a special meal for the old lady, whom none of them have ever seen for more than an instant. As the caterers grow in wisdom and sophistication, we learn that the lady may very well be an urbane ghost rather than a flesh-and-blood entity.

Two young lovers, offspring of the feuding Montague and Capulet families, value feelings above the past, pitting love and forgiveness against hatred and revenge.