You Lose You Die follows sociopathic tech expert, Mr. Fantastik, who runs a popular show on the dark web with two other sociopathic tech experts, Ms. Perfect and Mr. Creep. On the show, thousands of viewers vote on games and challenges for prisoners to participate in. If the prisoners lose, viewers vote on the weapons the sociopaths use to kill them.

Andrea visits her incarcerated son for the first time. Initially eyed with suspicion by other women in line, she gradually gains their trust — and emerges as a powerful advocate for justice reform.