A 1938 film.

Santa is a beautiful and very humble young girl living in Chimalistac, a small and quiet spot south of the 1930's Mexico City. After Santa is cheated by arrogant soldier Marcelino, she's rejected by her family and friends and expelled of Chimalistac. Santa finds shelter in a whorehouse and becomes a cinic and bitter woman, mistreated by bullfighter "Jarameno" and silently loved by blind pianist Hipolito.

In a small city, talented María was trained as a singer by blind composer Joaquín. They both dream of making it big in the capital but, when they finally make the move, they find that success is not achieved without struggles.