Chavela Vargas and Federico García Lorca are the main characters of this story. Poetry and music are the places of their meetings. Chavela explains when he lived in the same room where Federico García Lorca lived decades ago, was visited by a bird that contained the soul of the Spanish poet. In her last year of life, Chavela fulfills her last wish: to make a tribute to Spanish poet and finally meet him in the ranks of death. The Nightingale and the Night is a documentary that chronicles the transition from Chavela life to death, her union with Federico, dissolving the borders between reality and dreams.

Rafael Amargo is an artist who at the age of 35 feels his muses have abandoned him. Something many artists go through at some given moment. He feels a need to seek inspiration to rekindle the magic of the art fairy. This launches him on a journey that will take him to the source of such kind of inspiration, crossing seas, mountains and many roads until he arrives at the the refuge of the real protagonist of this film. His goal is to hand a letter from Lorca to the muse, Chavela Vargas.