When an alien contagion is released aboard a spaceship transforming its victims into demonic flesh-eaters, the crew must either destroy the infected or join them.

Based on actual accounts of werewolf sightings in Walworth County, Wisconsin, the film follows a local sheriff who is finally forced to accept that a string of horrifying deaths is linked to a predator which possesses DNA of both man and wolf.

Cal Weaver is living the American dream. He has a good job, a beautiful house, great children and a beautiful wife, named Emily. Cal's seemingly perfect life unravels, however, when he learns that Emily has been unfaithful and wants a divorce. Over 40 and suddenly single, Cal is adrift in the fickle world of dating. Enter, Jacob Palmer, a self-styled player who takes Cal under his wing and teaches him how to be a hit with the ladies.