2032 – After a large part of the female population was wiped out by a deadly virus five years ago, the government tries to stabilize the population with the help of surviving women. In order to achieve that, Jim and Cole have to track down and extradite surviving women. During a routine checkup, the two Blood Agents meet Mel Arcan, a disguised psychopath who tests their friendship.

Hank is a private investigator who retired from his detective job. But many years after his last case, he now needs to return to the job he once left, because an old evil has reawakened from his abyss.