On Broadway tells the story of Jack O'Toole, a 30-something Boston everyman, who writes a play about his dead uncle as a way to reconnect with his hard-nosed dad. With no money and just his gut to guide him, Jack quits his job as a carpenter so that he can mount a production of his play on the only stage he can afford: in the back room of his neighborhood pub, on a little street called Broadway.

Sixteen-year-old Dylan is dying of cancer. When a charitable organization offers to grant Dylan his final wish, the teen has a surprising request: to meet supermodel Nikki Sinclair. Much to his mother's dismay, Dylan, with the help of his best friends, goes to New York to fulfill his dream.

Bob Saginowski finds himself at the center of a robbery gone awry and entwined in an investigation that digs deep into the neighborhood's past where friends, families, and foes all work together to make a living - no matter the cost.

In an effort to tap into his original talent, a wheelchair-bound author moves to a rural town, where he befriends a single mother and her three kids, who help reignite his passion for writing.

A legendary late-night talk show host's world is turned upside down when she hires her only female staff writer. Originally intended to smooth over diversity concerns, her decision has unexpectedly hilarious consequences as the two women separated by culture and generation are united by their love of a biting punchline.