A gruesome homage to the cult Amicus anthology Asylum, Cradle of Fear unfolds four screamplays all linked by the unspeakable need of an incarcerated child killer to wreak vengeance on those responsible for his imprisonment. Helped by deranged angel Dani Filth, who leaves a trail of charnel house death in his crimson wake, the cannibal convict forces two Goth vamps to endure a one night stand from hell, two tough female robbers to see through each other, an obscenely rich coke-head to chop up more than a few lines and an internet surfer to descend into madness when he uncovers the ultimate web depravity.

In early 1860s New York, Irish immigrant Amsterdam Vallon is released from prison and returns to the Five Points, seeking revenge against his father's killer, William Cutting, a powerful anti-immigrant gang leader. He knows that revenge can only be attained by infiltrating Cutting's inner circle. Vallon's journey becomes a fight for personal survival and to find a place for the Irish people.