Would you go to therapy with crazy family members to collect millions? It wouldn't be as easy as you think. - When the family matriarch, Big Mama, passes away, her dying wish is to make sure the family she raised address their personal demons. Now, her dysfunctional family must seek unconventional therapy in order to get a multi-million dollar inheritance. Chaos ensues as they are forced to deal with old rivalries, volatile marriages, and failed dreams.

Chicago, the fight or flight mentality is focused on survival, a crew of girlfriends lost in trauma and grief from their past creates a robbery ring. However, things go bad when some high-profile politicians are brutally murdered, and the ladies find themselves the primary suspects.