Inventor Flint Lockwood creates a machine that makes clouds rain food, enabling the down-and-out citizens of Chewandswallow to feed themselves. But when the falling food reaches gargantuan proportions, Flint must scramble to avert disaster. Can he regain control of the machine and put an end to the wild weather before the town is destroyed?

The story of Gary Valentine and Alana Kane growing up, running around and going through the treacherous navigation of first love in the San Fernando Valley, 1973.

Decades since their successful television series was canceled, Chip has succumbed to a life of suburban domesticity as an insurance salesman. Dale, meanwhile, has had CGI surgery and works the nostalgia convention circuit, desperate to relive his glory days. When a former cast mate mysteriously disappears, Chip and Dale must repair their broken friendship and take on their Rescue Rangers detective personas once again to save their friend’s life.

In a 1960s-era informercial for an electric vibrating salad tossing device that, unbeknownst to the host, might have a dual purpose.

A sorority moves in next door to the home of Mac and Kelly Radner who have a young child. The Radner's enlist their former nemeses from the fraternity to help battle the raucous sisters.

A couple with a newborn baby face unexpected difficulties after they are forced to live next to a fraternity house.

Peter Klaven is a successful real estate agent who, upon getting engaged to the woman of his dreams, Zooey, discovers, to his dismay and chagrin, that he has no male friend close enough to serve as his Best Man. Peter immediately sets out to rectify the situation, embarking on a series of bizarre and awkward "man-dates."

When actress Sarah Marshall dumps aspiring musician Peter Bretter for rock star Aldous Snow, Peter's world comes crashing down. His best friend Brian suggests that Peter should get away from everything and to fly off to Hawaii to escape all his problems. After arriving in Hawaii and meeting the beautiful receptionist Rachel Jansen, Peter is shocked to see not only Aldous in Hawaii, but also Sarah.

When his new album fails to sell records, pop/rap superstar Conner4real goes into a major tailspin and watches his celebrity high life begin to collapse. He'll try anything to bounce back, anything except reuniting with his old rap group The Style Boyz.

A group of friends head to the land of oaky Chardonnays and big, bold Cabernet Sauvignons for one member of the squad’s 50th birthday party.